I used some Fablon in my van. Despite religiously squeezing out all the air between the mating surfaces.....it still bubbled. Probably due to the wide temperature variation within the van between winter and summer. In normal domestic application the temperature and humidity variation is probably quite small by comparison.
Suggest your wife thinks up other ways to keep you busy
When we bought a PVC we had a few years ago, the previous owns had left it with loads of old unused screw hole and damaged areas of walls where pictures had been, so I refurbished all of the interior panelling with DC-FIX which is a German manufactured version of Fablon. Even used it on the walls of the shower/loo and it handled the wet and temperature changes.
It made a fabulous looking job of our PVC and I was an expert at it by the time I had finished.